5. Know the range of functions that are served by the temporal lobes
6. Know the range of functions that are served by the occipital lobes
7. Know the range of functions that are served by the cerebellum
8. Know the range of functions that are served by the basal ganglia
9. Explain the theory of dual cortical streams for visual-spatial processing
10. Understand the layered and columnar organization of the normal neocortex
D. Genetics
1. Know how to characterize the different Mendelian modes of genetic inheritance
2. Understand genomic imprinting and its implications for genetic inheritance
3. Understand the pattern of inheritance associated with mitochondrial genetic disease
4. Understand the phenomenon of anticipation, associated with triplet repeat genetic
disease
5. Understand the concept of contiguous gene deletion syndromes
6. Understand the continuing interaction between genes and environment that influences
development and behavior
7. Understand the limitations in interpreting heritability parameter (h2) that is used in
population genetic studies
8. Differentiate between malformations and deformations
9. Know genetic mechanisms that contribute to the etiology of developmental and
behavioral disorders
10. Understand how to interpret a pedigree for genetic risk
11. Understand the concept of behavioral phenotypes
12. Understand the concept of uniparental disomy and its role in genetic disorders (eg,
Prader-Willi and Angelman syndromes)
13. Recognize developmental-behavioral disorders associated with single gene mutations
(Fragile X syndrome, Rett syndrome, Lesch-Nyhan syndrome, etc.)
14. Understand the epigenetic phenomenon of methylation and its implications for
developmental-behavioral disorders
15. Understand the concept of mutations or polymorphisms/copy number variations
E. Biological risk factors to neurobiological development
1. Understand how biomedical risk factors (eg, infection, trauma, hypoxia-ischemia,
toxins, nutritional deficiencies) jeopardize neurobiological development
2. Recognize factors that may mitigate biomedical risks to neurobiological development
(eg, other biological factors, genetic factors)
3. Recognize the phenotypic features of 22q.11.2 deletion syndrome
3. Family and Societal Factors
A. Structural factors
1. Recognize common challenges to the psychosocial development of children in blended
families (eg, insecurity associated with loss of a parent, difficulties with attachment to
a new parent, reactions to new siblings, inconsistent discipline practices, etc)
2. Understand how parental sexual orientation may impact childhood development
(academic achievement, psychological adjustment, and psychosexual development)
3. Understand typical reactions that children whose parents are separated or divorced
have to their families at various developmental stages